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Parathyroid

Webpages concerning "Parathyroid"

InteliHealth - Featuring Harvard Medical School's consumer health information. For more than 550 diseases and conditions, learn: What Is It?, Symptoms, Diagnosis, Expected Duration, Prevention, Treatment, When To Call A Professional, and Prognosis.
http://www.intelihealth.com/IH/ihtIH/WSIHW000/9339/24443.html
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http://www.intelihealth.com/IH/ihtIH/WSIHW000/9339/24443.html

Parathyroid Carcinoma - Parathyroid carcinoma is a rare malignancy of the parathyroid glands. These tumors secrete parathyroid hormone, thereby producing primary hyperparathyroidism. Parathyroid carcinoma may be suspected, but it usually cannot be confirmed prior to operation. This complicates the treatment ...
http://www.emedicine.com/med/topic1754.htm
Keywords:
parathyroid carcinoma, bone cyst, brown tumor, hyperparathyroidism, osteitis fibrosa cystica, pathologic fractures

http://www.emedicine.com/med/topic1754.htm

Expert-reviewed information summary about the treatment of parathyroid cancer.
http://www.cancer.gov/templates/doc_pdq.aspx?viewid=426E3A40-31E1-463F-A9EC-7036AA1CC6AB

http://www.cancer.gov/templates/doc_pdq.aspx?viewid=426E3A40-31E1-463F-A9EC-7036AA1CC6AB

New minimal parathyroid operation for requires 25 minutes and local anesthesia to cure parathyroid problems. Multiple parathyroid photos and text describing Minimally Invasive Radioguided Parathyroid Surgery (MIRP). Parathyroid disease and hyper-parathyroid-ism can be cured in 85\% as minimal outpatient surgery. Other operations for parathyroid glands are discused as well as all parathyroid diseas...
http://www.endocrineweb.com/MIRP.html
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http://www.endocrineweb.com/MIRP.html

Parathyroid cancer: diagnosis and treatment of parathyroid cancer. Parathyroid cancer information written by parathyroid expert doctors. Over 50 pages of parathyroid information written for parathyroid patients by parathyroid physicians.
http://www.endocrineweb.com/cancer.html
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http://www.endocrineweb.com/cancer.html

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Wikipedia-Article "Parathyroid"

The four human parathyroid glands are adjacent to the thyroid.
Enlarge
The four human parathyroid glands are adjacent to the thyroid.

The parathyroid glands are small endocrine glands in the neck, usually located within the thyroid gland, which produce parathyroid hormone. Most often there are four parathyroid glands but have been known to number six or eight.

Human parathyroid glands
Enlarge
Human parathyroid glands

Contents

Anatomy

The parathyroid glands are four small glands located on the posterior (closer to the back) surface of the thyroid gland. They distinguish themselves from the thyroid gland histologically as they contain two types of cells- parathyroid chief cells and oxyphil cells. Quite easily recognizable from the thyroid as it is has densly packed cell as contrasted by the follicle structure of the thyroid.

Physiology

Parathyroid hormone is a small protein that takes part in the control of calcium and phosphorus homeostasis, as well as bone physiology. When blood calcium levels drop below a certain point, calcium-sensing receptors in the parathyroid gland are activated to release hormone into the blood. It then stimulates osteoclasts to break down bone and release calcium into the blood. The sole purpose of the parathyroid glands is to regulate the calcium level in our bodies within a very narrow range so that the nervous and muscular systems can function properly.

Role in disease

Disorders of the parathyroid hormone receptor have been associated with Jansen's metaphyseal chondroplasia and Blomstrand's chondroplasia.

The single major disease of parathyroid glands is overactivity of one or more of the parathyroid lobes which make too much parathyroid hormone causing a potentially serious calcium imbalance. This is called hyperparathyroidism; it leads to hypercalcemia and osteitis fibrosa cystica. Since hyperparathyroidism was first described in 1925, the symptoms have become known as "moans, groans, stones, and bones." The primary treatment for this disease is the surgical removal of the faulty gland.

A Sestamibi scan is often used to determine which parathyroid gland(s) are responsible for overproduction of parathyroid hormone.

Embryology

The parathyroid glands originate from endoderm of the third and fourth pharyngeal pouches.

External links


Endocrine system
Adrenal gland - Corpus luteum - Hypothalamus - Ovaries - Pancreas - Parathyroid gland - Pineal gland - Pituitary gland - Testes - Thyroid gland
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