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Jem or JEM may refer to:

• Jem, a television animated series which aired in the mid-1980s
• Jem, the stage name of the musician Jemma Griffiths
• Jem, the 1980 book by Frederik Pohl
• a character in Harper Lee's To Kill a Mockingbird
• an Ibanez electric guitar designed by musician Steve Vai
• a nickname for James, Jeremiah or Jeremy
• The Journal of Environmental Monitoring or of Experimental Medicine

See also: Gem

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