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Cell Membrane and Adhesion

Webpages concerning "Cell Membrane and Adhesion"

A brief introduction to ion channels in biological membranes
http://www.omedon.co.uk/ionchan
Keywords:
ion, channels, membrane, specific, filter, specificity, potassium, calcium, sodium, toxins

http://www.omedon.co.uk/ionchan

Laboratory of Intracellular Ion Channels - Nencki Institute of Experimental Biology
http://www.nencki.gov.pl/iiclab/index.html
Keywords:
molecular, biology, proteins, membrane, ion, potassium, chloride, channel, intracellular, mitochondria, granules, chromaffin, reconstitution, cardioprotection, ischemia, preconditioning, sulfonylureas, openers, glibenclamide, diazoxide, atp

http://www.nencki.gov.pl/iiclab/index.html

This regularly updated website provides comprehensive information about the carcinoembryonic antigen (CEA) family in several species (human, mouse, rat and other), e. g. sequence information and domain structure graphs.
http://cea.klinikum.uni-muenchen.de
Keywords:
CEA, carcinoembryonic antigen, carcinoembryonic antigen family, CEACAM, PSG, pregnancy-specific glycoprotein, nomenclature, human, mouse, rat, guinea pig, baboon, African green monkey, Munich University

http://cea.klinikum.uni-muenchen.de

Explores the biophysics, structure and function of ion channels.
http://www.ionchannels.org/
Keywords:
ion channels, biophysics, electrophysiology

http://www.ionchannels.org/

Molecular Microbiology in the Department of Microbiology, University of Groningen, The Netherlands. Research interests: Transport across biological membranes.
http://molmic35.biol.rug.nl/
Keywords:
Secondary transport, membrane proteins, gene expression, Microbiology, Biochemistry, protein secretion, Transcription regulation, molecular biology, University of Groningen, Extremophiles, Sulfolobus, Thermophiles, Konings, Driessen, Multi Drug Resistance, Sec system, citrate transport, ATP driven transport, peptide transport, topology, glutamate transport, lipids, bacteria, Poolman, Lolkema, ...

http://molmic35.biol.rug.nl/

Home of membrane trafficking in neurons and epithelial cells
http://thierry.galli.free.fr/
Keywords:
neuron, membrane traffic, SNARE, TI-VAMP, VAMP7, VAMP-7, Sybl1, Synaptobrevin-like gene 1, VAMP, synaptobrevin, cellubrevin, synaptic vesicle, epithelial cell, axonal regeneration, INSERM, cell biology, research, Cell Physiology, Neurobiology, Exocytosis, Intracellular membrane, Neurites, Cell Movement, patent, exocytosis, endocytosis

http://thierry.galli.free.fr/

http://plab.ku.dk/tcbh/lectin-links.htm

http://plab.ku.dk/tcbh/lectin-links.htm

19-11-2004: Cell Membranes & Transport
http://www.eeyore.eclipse.co.uk/

http://www.eeyore.eclipse.co.uk/

http://celljunctions.med.nyu.edu/

http://celljunctions.med.nyu.edu/

http://dictybase.org/

http://dictybase.org/

http://integrins.hypermart.net/

http://integrins.hypermart.net/

http://dicty.cmb.northwestern.edu/green/

http://dicty.cmb.northwestern.edu/green/

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Wikipedia-Article "Adhesion"

Dew drops adhering to a spider web
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Dew drops adhering to a spider web

Adhesion is the molecular attraction exerted between bodies in contact. It is of particular interest to engineers who wish to stick things together and to biologists to understand the workings of cells.

Contents

Mechanisms of Adhesion

Five mechanisms have been proposed to explain why one material sticks to another:

Mechanical Adhesion

Two materials may be mechanically interlocked. Sewing forms a large scale mechanical bond, velcro forms one on a medium scale, and some textile adhesives form one at a small scale.

Chemical Adhesion

Two materials may form a compound at the join. The strongest joins are where atoms of the two materials swap (ionic bonding) or share (covalent bonding) outer electrons. A weaker bond is formed if oxygen, nitrogen or fluorine atoms of the two materials share a hydrogen nucleus (hydrogen bonding).

Dispersive Adhesion

Also known as Adsorption. Two materials may be held together by van der Waals forces. A van der Waals force is the attraction between two molecules that have positively and negatively charged ends. This positive and negative polarity may be a permanent property of a molecule (Keesom forces) or universally occurs in molecules, as the random movement of electrons within the molecules may result in a temporary concentration of electrons at one end (London forces).

Electrostatic Adhesion

Some conducting materials may pass electrons to form a difference in electrical charge at the join. This results in a structure similar to a capacitor and creates an attractive electrostatic force between the materials.

Diffusive Adhesion

Some materials may merge at the joint by diffusion. This may occur when the molecules of both materials are mobile and soluble in each other. This would be particularly effective with polymer chains where one end of the molecule diffuses into the other material. It is also the mechanism involved in sintering. When metal or ceramic powders are pressed together and heated, atoms diffuse from one particle to the next. This joins the particles into one.

What Makes an Adhesive Bond Strong?

The strength of the adhesion between two materials depends on which of the above mechanisms occur between the two materials, and the surface area over which the two materials contact. Materials that wet against each other tend to have a larger contact area than those that don't. Wetting depends on the surface energy of the materials.

See also

References

  • John Comyn, Adhesion Science, Royal Society of Chemistry Paperbacks, 1997
  • A.J. Kinloch, Adhesion and Adhesives: Science and Technology, Chapman and Hall, 1987
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